TY - JOUR T1 - Sjögren's syndrome-associated interstitial lung disease: A multicenter study JO - Reumatología Clínica (English Edition) T2 - AU - Reina,Delia AU - Roig Vilaseca,Daniel AU - Torrente-Segarra,Vicenç AU - Cerdà,Dacia AU - Castellví,Ivan AU - Díaz Torné,Cèsar AU - Moreno,Mireia AU - Narváez,Javier AU - Ortiz,Vera AU - Blavia,Rosana AU - Martín-Baranera,Montserrat AU - Corominas,Hèctor SN - 1699258X M3 - 10.1016/j.reuma.2015.09.003 DO - 10.1016/j.reuma.2015.09.003 UR - https://www.reumatologiaclinica.org/es-sjogren39s-syndrome-associated-interstitial-lung-disease-articulo-S1699258X15001564 AB - Primary Sjögren syndrome (PSS) is a chronic inflammatory autoimmune disease. Interstitial lung disease (ILD) can be an extraglandular complication. ObjectiveTo evaluate the clinical characteristics of patients diagnosed with PSS with ILD. MethodsMulticentre cohort study with 25 patients diagnosed with PSS and ILD. Data of PSS, prognostic factors, pulmonary involvement variables, complementary tests that suggest a worse diagnosis and treatment given were collected. EULAR index was measured for Sjögren's syndrome. ResultsWe identified 25 patients. In 15/25 the diagnosis of ILD was done before the diagnosis of PSS. The histopathological patterns found were: 12 NSIP, 5 UIP, 4 OP, 2 LIP. PFRs showed restrictive pattern. The majority of the patients received glucocorticoid therapy, antimalarial or immunosuppressive treatment. ConclusionsPatients affected with PSS must be screened to catch a precocious diagnosis of ILD. The majority of the patients were diagnosed of ILD before being diagnosed of PSS. Multicenter cohorts are increasingly demanded and a multidisciplinary management is needed. ER -