TY - JOUR T1 - Tuberculosis in Patients With Systemic Lupus Erythematosus: Spain's Situation JO - Reumatología Clínica (English Edition) T2 - AU - Arenas Miras,María del Mar AU - Hidalgo Tenorio,Carmen AU - Jimenez Alonso,Juan SN - 21735743 M3 - 10.1016/j.reumae.2012.06.026 DO - 10.1016/j.reumae.2012.06.026 UR - https://www.reumatologiaclinica.org/en-tuberculosis-in-patients-with-systemic-articulo-S2173574312001670 AB - There has recently been an increase in the incidence of patients with systemic lupus erythematosus (SLE) mainly due to earlier diagnosis, and increased survival. Tuberculosis in our country is one of the most prevalent infectious diseases, and one of the underlying causes would be HIV infection and increased immigration from areas with high tuberculosis prevalence; this phenomenon is truly important in patients with autoimmune diseases, as clinical presentation, severity and prognosis of tuberculosis are often different to that of immunocompetent patients. Studies of tuberculosis in patients with SLE are scarce and inconclusive, with many doubts existing about the performance or non-tuberculous prophylaxis in this population and the absence of a protocol due to lack of conclusive studies. New techniques for diagnosis of tuberculosis (IGRAs) may be useful in this population due to higher sensitivity than Mantoux, helping avoid false negatives. ER -