Original Article

DOI: 10.1016/j.reuma.2017.11.001

Rheumatoid factor testing in Spanish primary care: A population-based cohort study including 4.8 million subjects and almost half a million measurements

Uso del factor reumatoide en atención primaria en España: estudio de cohortes poblacionales incluyendo 4,8 millones de participantes y casi medio millón de mediciones

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Klara Morsleya, Anne Millerb, Raashid Luqmanic,

Corresponding author

raashid.luqmani@ndorms.ox.ac.uk

Corresponding author.

, Francesc Fina-Avilesd, Muhammad Kassim Javaidc, Christopher J. Edwardse, Rafael Pinedo-Villanuevac,f, Manuel Medinad, Sebastian Calerod, Cyrus Cooperc,f,g, Nigel Ardenc, Daniel Prieto-Alhambrac,h

a Department of Rheumatology, Royal Berkshire Hospital, The Royal Berkshire NHS Foundation Trust, United Kingdom

b Department of Rheumatology, Nuffield Orthopaedic Centre, Oxford University Hospitals NHS Trust, United Kingdom

c Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, United Kingdom

d Direcció de Sistemes d’Informació, Institut Català de la Salut, Barcelona, Spain

e NIHR Wellcome Trust Clinical Research Facility, University of Southampton, United Kingdom

f MRC Lifecourse Epidemiology Unit, United Kingdom

g Faculty of Medicine, University of Southampton, United Kingdom

h GREMPAL Research Group, Idiap Jordi Gol and CIBERFes, Universitat Autonoma de Barcelona and Instituto de Salud Carlos III, Barcelona, Spain