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Vol. 22. Issue 3.
(March 2026)
Brief Report

Prevalence of comorbidities and medication use in progressive systemic sclerosis in northeast Mexico

Prevalencia de comorbilidades y uso de medicamentos en la esclerosis sistémica progresiva en el noreste de México
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Jorge Armando Hermosillo-Villafrancaa,
Corresponding author
jorge.h.villafranca@gmail.com

Corresponding author.
, Maria Joselin Rodarte-Gallegosb
a Servicio de Reumatología, Hospital general de Zona #11, Instituto Mexicano del Seguro Social, Piedras Negras, Coahuila, Mexico
b Servicio de Reumatología, Unidad Médica de Alta Especialidad #71, Instituto Mexicano del Seguro Social, Torreón, Coahuila, Mexico
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Abstract
Background

Systemic sclerosis (SSc) is characterized by exuberant fibrosis, caused by severe vasculopathy and vasospasm. Despite the impact of the disease on survival, epidemiological and comorbidity data on SSc are currently limited in Mexico.

Methods

Observational, cross-sectional, and descriptive clinical study. Patients with SSc according to the 2013 ACR/EULAR criteria from 2 public healthcare centres in northeastern Mexico from the IMSS were included. Sociodemographic, clinical, and laboratory variables were collected. The prevalence of comorbidities reported by the patients was investigated. Serology, transthoracic ultrasound, and high-resolution chest computed tomography were performed.

Results

68 patients with SSc were included: 65 (95.3%) women, with a mean age of 51.5 ± 9.86 years, with the following distribution: 50 (73.5%) limited, 7 (10.3%) diffuse, 11 overlap (16.2%), 22 (32.3%) with systemic arterial hypertension, 14 (20.5%) with obesity.

Conclusions

The detection of systemic arterial hypertension, the most frequent comorbidities in multiple populations, could prevent cardiovascular complications.

Keywords:
Systemic sclerosis
Scleroderma
Systemic arterial hypertension
Comorbidity
Epidemiology
Resumen
Introducción

La esclerosis sistémica (ES) se caracteriza por una fibrosis exuberante, que se origina por una vasculopatía y vasoespasmo grave, A pesar del impacto de la enfermedad en la supervivencia los datos de epidemiología y comorbilidades en la ES hasta el momento son limitados en México.

Materiales y métodos

Estudio clínico observacional, transversal y descriptivo. Se incluyeron pacientes con ES según los criterios ACR/ EULAR 2013 de 2 centros de atención pública del noreste de México del IMSS, Se recogieron variables sociodemográficas, clínicas y analíticas Se investigaron la prevalencia de comorbilidades reportadas por los pacientes, Se Realizó Serología, Ecografía transtorácica y la Tomografía de alta resolución de tórax.

Resultados

Se incluyeron 68 pacientes con ES 65 (95.3%) Mujeres, con una edad media de 51.5 ± 9.86 Años, con la siguiente distribución: 50 (73.5%) limitada, 7 (10.3%) difusa, 11 (16.2%) con sobreposicion, 22 (32.3%) con Hipertensión Arterial sistémica, 14 (20.5%) con obesidad.

Conclusiones

La detección de hipertensión arterial sistémica la más frecuente de las comorbilidades en múltiples poblaciones podría prevenir complicaciones cardiovasculares.

Palabras clave:
Esclerosis sistémica
Esclerodermia
Hipertensión arterial sistémica
Comorbilidad
Epidemiología

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