Journal Information
Vol. 4. Issue 6.
Pages 240-247 (November - December 2008)
Share
Share
Download PDF
More article options
Vol. 4. Issue 6.
Pages 240-247 (November - December 2008)
Full text access
Responsiveness of Outcome Measures
Sensibilidad al cambio de las medidas de desenlace
Visits
5066
María Jesús García de Yébenes Prousa,
Corresponding author
mjesus.garciadeyebenes@ser.es

Correspondence: Unidad de Investigación. Fundación Española de Reumatología. Marqués del Duero, 5, 1.° A. 28001 Madrid. España.
, Francisco Rodríguez Salvanésb, Loreto Carmona Ortellsa
a Unidad de Investigación, Fundación Española de Reumatología, Madrid, Spain
b Agencia Laín Entralgo, Madrid, Spain
This item has received
Article information
Abstract

In medical research, particularly in the field of rheumatology, there is great interest about the concept of responsiveness of outcome measures as a sign of changes in the patient's health status. However, the terminology surrounding this concept and the methods of analysis are confusing and lacking in consensus.

We present a review about the concept and analysis of responsiveness taking into account both, the characteristics of the responsiveness and the type of design and predictable change in the sample being studied.

Key words:
Responsiveness
Outcome measures
Responsiveness statistics
Resumen

En la investigación médica, y en especial en el ámbito de la reumatología, hay gran interés sobre el concepto de sensibilidad al cambio de un instrumento de medida como posible reflejo de modificaciones en la situación clínica del paciente. Sin embargo, la terminología de este concepto y su metodología de análisis están rodeadas de confusión y falta de consenso.

Se presenta un trabajo de revisión sobre el concepto y el análisis de la sensibilidad al cambio teniendo en cuenta tanto las características de la sensibilidad como el tipo de diseño y cambio previsible en la muestra en estudio.

Palabras clave:
Sensibilidad al cambio
Medidas de desenlace
Estadísticos de sensibilidad al cambio
Full text is only aviable in PDF
References
[1.]
G.H. Guyatt, B. Kirshner, R. Jaeschke.
Measuring health status: what are the necessary measurement properties?.
J Clin Epidemiol, 45 (1992), pp. 1341-1345
[2.]
C.B. Terwee, F.W. Dekker, W.M. Wiersinga, M.F. Prummel, P.M. Bossuyt.
On assessing responsiveness of health-related quality of life instruments: guidelines for instrument evaluation.
Qual Life Res, 12 (2003), pp. 349-362
[3.]
D.E. Beaton, S. Hogg-Johnson, C. Bombardier.
Evaluating changes in health status: reliability and responsiveness of five generic health status measures in workers with musculoskeletal disorders.
J Clin Epidemiol, 50 (1997), pp. 79-93
[4.]
G.R. Norman, P. Stratford, G. Regehr.
Methodological problems in the retrospective computation of responsiveness to change: the lesson of Cronbach.
J Clin Epidemiol, 50 (1997), pp. 869-879
[5.]
J.A. Husted, R.J. Cook, V.T. Farewell, D.D. Gladman.
Methods for assessing responsiveness: a critical review and recommendations.
J Clin Epidemiol, 53 (2000), pp. 459-468
[6.]
T.L. Walsh, B. Hanscom, J.D. Lurie, J.N. Weinstein.
Is a condition-specific instrument for patients with low back pain/leg symptoms really necessary? The responsiveness of the Oswestry Disability Index, MODEMS, and the SF-36.
[7.]
H.C. de Vet, L.M. Bouter, P.D. Bezemer, A.J. Beurskens.
Reproducibility and responsiveness of evaluative outcome measures. Theoretical considerations illustrated by an empirical example.
Int J Technol Assess Health Care, 17 (2001), pp. 479-487
[8.]
P.W. Stratford, D.L. Riddle.
Assessing sensitivity to change: choosing the appropriate change coefficient.
Health Qual Life Outcomes, 3 (2005), pp. 23
[9.]
E.T. Koh, K.P. Leong, I.Y. Tsou, et al.
The reliability, validity and sensitivity to change of the Chinese version of SF-36 in oriental patients with rheumatoid arthritis.
Rheumatology (Oxford), 45 (2006), pp. 1023-1028
[10.]
D.E. Beaton, C. Bombardier, J.N. Katz, J.G. Wright.
A taxonomy for responsiveness.
J Clin Epidemiol, 54 (2001), pp. 1204-1217
[11.]
M. Corzillius, P. Fortin, G. Stucki.
Responsiveness and sensitivity to change of SLE disease activity measures.
Lupus, 8 (1999), pp. 655-659
[12.]
M.H. Liang, A.H. Fossel, M.G. Larson.
Comparisons of five health status instruments for orthopedic evaluation.
Med Care, 28 (1990), pp. 632-642
[13.]
D.E. Beaton, M. Boers, G.A. Wells.
Many faces of the minimal clinically important difference (MCID): a literature review and directions for future research.
Curr Opin Rheumatol, 14 (2002), pp. 109-114
[14.]
R.A. Deyo, R.M. Centor.
Assessing the responsiveness of functional scales to clinical change: an analogy to diagnostic test performance.
J Chronic Dis, 39 (1986), pp. 897-906
[15.]
P.W. Stratford, F.M. Binkley, D.L. Riddle.
Health status measures: strategies and analytic methods for assessing change scores.
Phys Ther, 76 (1996), pp. 1109-1123
[16.]
G.R. Norman.
Issues in the use of change scores in randomized trials.
J Clin Epidemiol, 42 (1989), pp. 1097-1105
[17.]
F. Salaffi, A. Stancati, R. Neri, W. Grassi, S. Bombardieri.
Measuring functional disability in early rheumatoid arthritis: the validity, reliability and responsiveness of the Recent-Onset Arthritis Disability (ROAD) index.
Clin Exp Rheumatol, 23 (2005), pp. S31-S42
[18.]
M.M. Veehof, P.M. Ten Klooster, E. Taal, P.L. van Riel, M.A. van de Laar.
Psychometric properties of the Rheumatoid Arthritis Disease Activity Index (RADAI) in a cohort of consecutive Dutch patients with RA starting antitumour necrosis factor treatment.
Ann Rheum Dis, 67 (2008), pp. 789-793
[19.]
J.G. Wright, N.L. Young.
A comparison of different indices of responsiveness.
J Clin Epidemiol, 50 (1997), pp. 239-246
[20.]
J. Fransen, H. Hauselmann, B.A. Michel, M. Caravatti, G. Stucki.
Responsiveness of the self-assessed rheumatoid arthritis disease activity index to a flare of disease activity.
Copyright © 2008. Sociedad Española de Reumatología and Colegio Mexicano de Reumatología
Idiomas
Reumatología Clínica (English Edition)
Article options
Tools
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?