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Vol. 5. Issue 1.
Pages 31-33 (January - February 2009)
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Vol. 5. Issue 1.
Pages 31-33 (January - February 2009)
DOI: 10.1016/S2173-5743(09)70085-1
Sarcoidosis-Lymphoma Syndrome
Síndrome sarcoidosis-linfoma
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Elisabet García Casaresa,??
Corresponding author
37710egc@comb.es

Corresponding author.
, Lourdes Mateo Soriaa, Emma García Melchora, Sonia Mínguez Blascoa, Ferran Vall-Llobera Calmetb, Gerónima Cañellas Olivera, Susana Holgado Péreza
a Sección de Reumatología, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain
b Servicio de Hematología, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain
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Abstract

Sarcoidosis may occur in association with lymphoma (sarcoidosis-lymphoma syndrome), it is an uncommon but well-known association. Some clinical features can be similar and clinicians have the challenge to differentiate between these 2 diseases or prove their co-existence. Clinical and laboratory data are not characteristic in any of them, and an anatomopathological study of lymphadenopathy is necessary to establish the diagnosis. The sarcoidosis-lymphoma syndrome could occur as a result of a disturbance in the host immune system in sarcoidosis and in some patients with solid tumors or hematologic malignancies who have received chemotherapy. We present a case report of a patient with sarcoidosis-lymphoma syndrome.

Keywords:
Granuloma
Sarcoidosis
Lymphoma
Resumen

La combinación de sarcoidosis y linfoma (síndrome sarcoidosis-linfoma) es poco frecuente pero bien conocida. Algunas manifestaciones pueden ser comunes y es un reto para el clínico establecer el diagnóstico diferencial entre ambas entidades o de su verdadera coexistencia. En estos casos ni la presentación clínica ni los parámetros de laboratorio son específicos, por lo que es esencial el estudio anatomopatológico de una adenopatía para llegar al diagnóstico definitivo. El síndrome sarcoidosis-linfoma podría aparecer como consecuencia de algunas alteraciones inmunitarias que acontecen en la sarcoidosis y en algunos pacientes con una neoplasia sólida o hemática que reciben quimioterapia. Se presenta un caso de síndrome sarcoidosis-linfoma y se analizan los aspectos clave en el diagnóstico de esta forma clínica.

Palabras clave:
Adenopatía
Granuloma
Sarcoidosis

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