Clinical StudyLack of effect of antibiotics on biopsy culture results in vertebral osteomyelitis
References (6)
- et al.
Percutaneous needle biopsy in diagnosis and identification of causative organisms in cases of suspected vertebral osteomyelitis
Eur J Radiol
(2012) - et al.
2015 Infectious Diseases Society of America (IDSA) clinical practice guidelines for the diagnosis and treatment of native vertebral osteomyelitis in adults
Clin Infect Dis
(2015) - et al.
Lancet
(2015)
Cited by (11)
A Comparison of CT-Guided Bone Biopsy and Fluoroscopic-Guided Disc Aspiration as Diagnostic Methods in the Management of Spondylodiscitis
2022, Current Problems in Diagnostic RadiologyCitation Excerpt :Antibiotics are often held before percutaneous biopsies due to prior evidence suggesting lower yield if given before intervention.15,22-25 However, more recent evidence seems to refute this,26,27 and our results similarly found that antibiotic administration did not negatively impact yield (OR 0.83: 95% CI, 0.35-2.00). This is likely because the duration of pre-procedure antibiotics was generally short (<72hours).
CT-Guided Needle Biopsy in Vertebral Osteomyelitis: Study of Factors That Could Influence in Culture Yield
2022, Reumatologia ClinicaCitation Excerpt :This result might be linked to the higher presence of further surgical approach detected in the negative culture group. As it has been pointed out in several studies delay in diagnosis is probably the main issue in VO.2,17 Moreover, since antibiotic withholding is widely recommended,1 these biopsies should be performed as soon as possible.
Diagnostic Performance of CT-Guided Bone Biopsies in Patients with Suspected Osteomyelitis of the Appendicular and Axial Skeleton with a Focus on Clinical and Technical Factors Associated with Positive Microbiology Culture Results
2020, Journal of Vascular and Interventional RadiologyCitation Excerpt :The high concordance of positive blood and biopsy cultures within the AS can be associated with its pathogenic mechanism, which is usually hematogenous seeding (25). Similar to this work, several previous studies showed that antimicrobial therapy administered before the bone biopsies did not affect the microbiology yield (7,8,13,18,26–29). In accordance with the Infectious Diseases Society of America guidelines (17), patients were defined to be on antibiotic/antimicrobial therapy if they received a dose of antimicrobials within 48 hours before the biopsy.
Hot topics on vertebral osteomyelitis from the International Society of Antimicrobial Chemotherapy
2019, International Journal of Antimicrobial AgentsProgress in the diagnosis and treatment of secondary spinal infection after solid organ transplantation
2022, Chinese Journal of Clinical Infectious DiseasesMissed Opportunities for Diagnosing Vertebral Osteomyelitis Caused by Influential Cognitive Biases
2022, American Journal of Case Reports