Thoracic transplantationHeartCommon Occurrence of Everolimus-Associated Aphthous Stomatitis in Japanese Heart Transplant Recipients
Heart
Section snippets
Case Reports
Clinical characteristics of the heart transplant recipients who were treated with the switch to EVL are shown in Table 1.
Discussion
Although the occurrence of EVL-associated aphthous stomatitis has not yet been described in the global literature, there have been several reports of sirolimus-associated aphthous stomatitis.10, 11, 12, 13 Ram et al reported a kidney transplant recipient who developed severe aphthous stomatitis after the administration of sirolimus whose disorder was cured by a switch to EVL.14
Aphthous stomatitis associated with sirolimus has been reported in 9% of psoriatic patients who received sirolimus.10
Acknowledgment
This work was supported by grants from Japan Cardiovascular Research Foundation and grants from the Japan Heart Foundation.
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