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Vol. 15. Issue 5.
Pages e18-e20 (September - October 2019)
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Vol. 15. Issue 5.
Pages e18-e20 (September - October 2019)
Case report
DOI: 10.1016/j.reumae.2017.04.010
Coexistence of sarcoidosis and adult onset Still disease
Coexistencia de sarcoidosis y enfermedad de Still del adulto
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Huseyin Semiza, Senol Kobakb,
Corresponding author
senolkobak@gmail.com

Corresponding author.
a Ege University, Faculty of Medicine, Department of Internal Medicine, Turkey
b Istinye University, Faculty of Medicine, Department of Rheumatology, Turkey
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Table 1. Sarcoidosis vs. adult onset Still's disease – common similarities.
Abstract

Sarcoidosis is a chronic, inflammatory disease with unknown cause characterized by non-caseating granuloma formations. It can be presented with bilateral hilar lymphadenopathy, skin lesions, eye involvement and locomotor system findings. Adult onset Still disease (AOSD) is a chronic inflammatory disease which presents with fever, arthritis and typical skin rashes. The disease is rare and can be misdiagnosed due to the absence of typical clinical and laboratory findings. The association of sarcoidosis and AOSD has not been previously reported in the literature.

Herein we reported the development of AOSD in a patient followed by the diagnosis of sarcoidosis. The patient did not respond to high-dose corticosteroids and methotrexate therapy, and the disease was under control with anti-IL-6 (Tocilizumab) drug.

Keywords:
Sarcoidosis
Adult onset Still's disease
Coexistence
Resumen

La sarcoidosis es una enfermedad inflamatoria crónica de causa desconocida, que se caracteriza por formaciones de granulomas no caseificantes. Puede presentarse como linfadenopatía hiliar bilateral, lesiones cutáneas, compromiso ocular y del sistema locomotor. La enfermedad de Still del adulto (AOSD) es una enfermedad inflamatoria crónica que se presenta con fiebre, artritis y erupciones cutáneas típicas. Dicha enfermedad es rara y puede diagnoticarse erróneamente debido a la ausencia de rasgos clínicos y de laboratorio típicos. En la literatura no se ha reportado previamente la asociación entre sarcoidosis y AOSD.

Reportamos aquí el desarrollo de AOSD en un paciente sometido a seguimiento debido a diagnóstico de sarcoidosis. El paciente no respondió al tratamiento con altas dosis de corticosteroides y metotrexato, manteniéndose la enfermedad bajo control con un fármaco anti-IL-6 (Tocilizumab).

Palabras clave:
Sarcoidosis
Enfermedad de Still del adulto
Coexistencia

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