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Vol. 19. Issue 6.
Pages 348 (June - July 2023)
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Vol. 19. Issue 6.
Pages 348 (June - July 2023)
Images in Clinical Rheumatology
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Freiberg disease: A rare cause of chronic foot pain
Enfermedad de Freiberg: una causa rara de dolor crónico en los pies
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Daniela Oliveiraa,b,c,
Corresponding author
danielasoff@gmail.com

Corresponding author.
, Lúcia Costaa, Carlos Vaza,b,c
a Rheumatology Department, University Hospital Center of São João, Porto, Portugal
b Department of Medicine of Faculty of Medicine, University of Porto, Porto, Portugal
c Center for Health Technology and Services Research (CINTESIS), Faculty of Medicine, University of Porto, Porto, Portugal
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Non-weightbearing (Fig. 1A) and weightbearing (Fig. 1B) anteroposterior radiographs demonstrated a Freiberg disease in a 78-year-old female patient with forefoot chronic pain, swelling and restricted motion of the right third metatarsophalangeal joint. Laboratory results revealed normal inflammatory parameters. Radiographs images showed reduction in the height of the articular interline (Fig. 1A), subchondral sclerosis and flattening (Fig. 1B) of right third metatarsophalangeal head compatible with an avascular necrosis of right third metatarsal head. The patient was improved with daily activity and shoe wear modifications combined with an oral nonsteroidal anti-inflammatory drug. Freiberg disease is a rare clinical condition characterized by avascular necrosis of metatarsal head, most commonly the second metatarsal. The etiology of this condition is multifactorial, involving traumatic causes, vascular compromise and systemic disorders such as systemic lupus erythematosus. The differential diagnostic based on clinical presentation and radiograph findings is crucial and include stress fracture, neuroma, rheumatoid arthritis and gout. Conservative management, namely rest, activity and/or shoes modifications and analgesia aims to control pain and prevent progression. However, when these interventions are ineffective, surgical treatment may be indicated.

Fig. 1.

Non-weighbearing (A) and weightbearing (B) anteroposterior radiographs of the patient's foot, representing avascular necrosis of right third metatarsal head (red circles).

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Conflicts of interest

The authors declare that they have no conflicts of interest.

Copyright © 2022. Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología
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Reumatología Clínica (English Edition)
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