Response of the author to the letter “Cost-effectiveness study of leflunomide versus methotrexate” Antonio J. García Ruiz, Ana C. Montesinos Gálvez, Lucía Pérez Costillas, Pablo Rebollo

Systematic review and meta-analysis of the efficacy and safety of leflunomide and methotrexate in the treatment of rheumatoid arthritis Roberto Alfaro-Lara, Hector Fabricio Espinosa-Ortega, César Alejandro Arce-Salinas

A comparison of leflunomide and subcutaneous methotrexate in the treatment of rheumatoid arthritis: an approximation based on the number needed to treat Antonio J. Garcia Ruiz, Ana C. Montesinos Galvez, Lucia Perez Costillas, Pablo Rebollo