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Vol. 8. Issue 5.
Pages 284-286 (September - October 2012)
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Vol. 8. Issue 5.
Pages 284-286 (September - October 2012)
Case Report
DOI: 10.1016/j.reumae.2011.11.007
Reactive Arthritis After the Intravesical Instillation of BCG
Artritis reactiva secundaria a la instilación intravesical de bacilo de Calmette-Guérin
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Cristina Macía Villa??
Corresponding author
ccmacia@gmail.com

Corresponding author.
, Walter Sifuentes Giraldo, Alina Boteanu, Mariano González Lanza, Javier Bachiller Corral
Servicio de Reumatología, Hospital Universitario Ramón y Cajal, Madrid, Spain
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Abstract

The intravesical instilation of bacillus Calmette-Guérin (BCG) is a widely used and efficacious procedure for treatment of intermediate to high-grade superficial bladder cancer. The occurrence of osteoarticular side effects is infrequent compared to the number of administrated doses, and reactive arthritis is included within these effects. We present the case of a 54 years old HLA-27 (+) male, who developed reactive arthritis featuring asymmetric olygoarthritis and dactylitis after the second intravesical BCG instillation, which was resolved with administration of Etoricoxib and Isoniazid.

Keywords:
Reactive arthritis
Bacillus de Calmette-Guérin
Dactylitis
Enthesopathy
HLA-B27
Resumen

La instilación intravesical de bacilo de Calmette-Guérin (BCG) es un procedimiento ampliamente utilizado y eficaz para el tratamiento del carcinoma vesical superficial de grado intermedio y alto. La aparición de efectos colaterales osteoarticulares es infrecuente comparado con el número de dosis administradas, y dentro de estos se incluye la artritis reactiva. Presentamos el caso de un paciente varón de 54 años, HLA B27 (+), que desarrolló un cuadro de artritis reactiva caracterizado por oligoartritis asimétrica y dactilitis tras la segunda instilación intravesical de BCG, y que se resolvió con el tratamiento con etoricoxib e isoniazida.

Palabras clave:
Artritis reactiva
Bacilo de Calmette-Guérin
Dactilitis
Entesopatía
HLA-B27

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