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Vol. 9. Issue 3.
Pages 178-180 (May - June 2013)
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Vol. 9. Issue 3.
Pages 178-180 (May - June 2013)
Case report
DOI: 10.1016/j.reumae.2012.06.025
Tocilizumab in a Patient With Tophaceous Gout Resistant to Treatment
Tocilizumab en paciente con gota tofácea severa refractaria al tratamiento
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Jessica L. Pinto, Gloria E. Mora, Daniel G. Fernández-Avila??
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danielfernandezmd@gmail.com

Corresponding author.
, Juan M. Gutiérrez, María C. Díaz, Grupo Javeriano de Investigación en Enfermedades Reumáticas
Unidad de Reumatología, Departamento de Medicina Interna, Hospital Universitario San Ignacio, Pontificia Universidad Javeriana, Bogotá, Colombia
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Table 1. Monitoring Activity of Disease During Treatment.
Abstract

Gout is a disease characterized by acute episodes of pain, which occurs as the result of monosodic urate crystal deposit in the joint and periarticular tissue. In some cases, gout behaves as a severe inflammatory arthopathy that is difficult to manage, generating structural joint damage and functional impairment. We report the case of a 44 years old man with gouty arthritis for 12 years, not responding to NSAIDs, alopurinol, colchicine or corticosteroids. Tocilizumab was started with favorable clinical and laboratory results after treatment.

Keywords:
Severe tophaceous gout
Rheumatoid arthritis
Tocilizumab
Resumen

La gota es una enfermedad que se caracteriza por episodios agudos de dolor como consecuencia del depósito de cristales de urato monosódico en las articulaciones y en el tejido periarticular. En algunos casos, la gota se comporta como una artropatía inflamatoria severa de difícil manejo, generándose daño estructural articular y alteración funcional secundaria. Presentamos el caso de un hombre de 44 años con artritis gotosa tofácea severa de 12 años de evolución, sin respuesta al manejo con AINE, alopurinol, colchicina y corticoides, a quien se inició tratamiento con tocilizumab, con favorable respuesta clínica y paraclínica.

Palabras clave:
Gota
Inflamación
Tocilizumab

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