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Vol. 11. Núm. 4.
Páginas 252-254 (Julio - Agosto 2015)
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Vol. 11. Núm. 4.
Páginas 252-254 (Julio - Agosto 2015)
Images in Clinical Rheumatology
DOI: 10.1016/j.reumae.2014.12.003
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Giant Cell Tumor of the Tendon Sheaths of the Fingers
Tumor de células gigantes de las vainas tendinosas de los dedos de la mano
Luis R. Ramos-Pascua
Autor para correspondencia

Corresponding author.
, Omar A. Guerra-Álvarez, Paula Casas-Ramos, Francisco Arias-Martín
Servicio de Cirugía Ortopédica y Traumatología, Complejo Asistencial Universitario de León, Gerencia Regional de Salud de Castilla y León (SACYL), León, Spain
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Clinical Case Presentation

The case was a male patient, 65 years old, with no relevant medical history, who was consulted due to painless swelling on the dorsal side of the fifth finger of the left hand which had lasted for 4 years, with no history of trauma. Physical examination confirmed the tumor, elastic on palpation, with preserved finger mobility (Fig. 1) Simple X-rays showed a soft tissue tumor (Fig. 2); the ultrasound demonstrated the same lesion and the MRI showed a lesion measuring 16×10×12mm in diameter craneo-caudally, anteroposterior and transversely, unhomogeneous, with a hypointense signal and loculations on T1, predominantly hyperintense on T2 and showing moderate contrast enhancement (Fig. 3).

Fig. 1.

Clinical appearance of the fifth finger of the patient.

Fig. 2.

Simple X-ray AP (A) and lateral projections (B), with an increase in density corresponding to the lesion, with indemnity of the phalangeal soft tissue.

Fig. 3.

Axial MRI scanning, showing a hypointense lesion on T1 (A) and hyperintense on T2 (B), with slight enhancement after contrast administration (C).

Diagnosis and Evolution

The lesion was diagnosed to be a giant cell tumor of the tendon sheath of the fifth finger and was removed in its entirety (Fig. 4). Two years later the lesion recurred (Fig. 5) and the patient underwent surgery. Currently, after two years, there have been no new recurrences, the mobility of the distal interphalangeal joint is limited, although the function of the patient's hand is normal.

Fig. 4.

Macroscopic appearance of the lesion, after excision of nodular tissue and of a yellow-brownish color.

Fig. 5.

Lesional recurrence 2 years after resection.


The TSGCT of unknown etiology, excluding ganglia, represent almost half of the soft tissue tumors of the hand.1 It is common to find nodular forms and they occur in patients 30–50 years of age, although with a wide age range, being often female (in 55%–70% of cases). They are usually found on the volar side, the laterovolar side or the fingers, especially in the vicinity of the distal interphalangeal joint, without preference for a particular finger.1–6 Regarding laterality, the lesion is more common on the right and the dominant hand.4,6

The suspected diagnosis of TSGCT of the hand is made clinically and through complementary imaging tests, including simple radiographs and ultrasound, which are usually sufficient, and no biopsy is needed. Clinically, it is suspected when documenting a solitary soft tissue nodule that respects the skin, is often eccentric, painless and slow-growing.1 1%–24% of patients report some pain,3,4,6 usually in conjunction with increased volume and, sometimes, neurovascular compromise. The clinical differential diagnosis is extensive. Ultrasound identifies a generally homogeneous, hypo- or hyperechoic solid lesion or, rarely, a heterogeneous one, with increased vascularity on Doppler study, and in relation to the tendon sheath, with which it does not move for that reason.6–8 It is also common to find satellite lesions, and although this lesion could be confused with a ruptured synovial cysts, confusion has no therapeutic significance if intervened upon. Among complementary imaging, MRI is considered by some to be the most accurate imaging test for diagnosis.4,7,8

Treatment of TSGCT is based on the complete removal of the lesion. The technique seems more reliable using a large exposition and using magnifying glasses or microsurgical tools.6,9 Radiation therapy, although controversial, could be indicated in cases with higher risk of recurrence (lesions with mitosis, bone involvement or incomplete resection). This occurs in up to 45% of treated cases.

The authors declare that they have read and approved the manuscript and that the requirements for authorship have been met.

Ethical disclosuresProtection of human and animal subjects

The authors declare that no experiments were performed on humans or animals for this study.

Confidentiality of data

The authors declare that they have followed the protocols of their work center on the publication of patient data.

Right to privacy and informed consent

The authors have obtained the written informed consent of the patients or subjects mentioned in the article. The corresponding author is in possession of this document.

Conflict of Interest


E. Bartolomé-del Valle, A. García-Olea, J. González-del Pino, A. Lovic, A. Dudley-Porras.
Tumores primarios de partes blandas de la mano. Análisis epidemiológico de 305 casos.
Rev Ortop Traumatol, 42 (1998), pp. 418-426
E. Fotiadis, A. Papadopoulos, T. Svarnas, P. Akritopoulos, N.P. Sachinis, B.E. Chalidis.
Giant cell tumour of tendon sheath of the digits. A systematic review.
H. Chougri, A. Moussaoui, J. Nonnenmacher.
Giant cell tumor of the tendon sheath with introsseous phalangeal invasion: a case report and review of the literature.
Eur J Orthop Surg Traumatol, 15 (2005), pp. 151-156
F.M. Darwish, W.H. Haddad.
Giant cell tumour of tendon sheath: experience with 52 cases.
Singap Med J, 49 (2008), pp. 879-882
B. Garg, P.P. Kotwal.
Giant cell tumour of the tendon sheath of the hand.
J Orthop Surg, 19 (2011), pp. 218-220
M. Lautenbach, S. Kim, M. Millrose, A. Eisenschenk.
Nodular giant cell tumour of the tendon sheath of the hand: analysis of eighty-four cases – diagnostic decisions and outcome.
Int Orthop, 37 (2013), pp. 2211-2215
E. Bassetti, R. Candreva, E. Santucci.
Giant cell tumor of the flexor tendon of the wrist: US and MRI evaluation. Case report.
J Ultrasound, 14 (2011), pp. 37-39
A. Bargiela.
Utilidad de la ecografía en el estudio de la enfermedad sinovial.
Radiología, 52 (2010), pp. 301-310
S.S. Suresh, H. Zaki.
Giant cell tumor of tendon sheath: case series and review of literature.
J Hand Microsurg, 2 (2010), pp. 67-71

Please cite this article as: Ramos-Pascua LR, Guerra-Álvarez OA, Casas-Ramos P, Arias-Martín F. Tumor de células gigantes de las vainas tendinosas de los dedos de la mano. Reumatol Clin. 2015;11:252–254.

Copyright © 2014. Elsevier España, S.L.U.. All rights reserved
Reumatología Clínica

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