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Vol. 12. Issue 4.
Pages 196-200 (July - August 2016)
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Vol. 12. Issue 4.
Pages 196-200 (July - August 2016)
Original Article
DOI: 10.1016/j.reumae.2016.04.003
Burden and Direct Costs of Non Infectious Uveitis in Spain
Carga y costes directos de la uveítis no infecciosa en España
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Alfredo Manuel Adán-Civeraa,
Corresponding author
, José Manuel Benítez-del-Castillob, Ricardo Blanco-Alonsoc, Esperanza Pato-Courd, Agustí Sellas-Fernándeze, Antonio Bañares-Cañizaresf
a Institut Clínic d’Oftalmologia, Hospital Clínic de Barcelona, Barcelona, Spain
b Unidad de Superficie e Inflamación Ocular, Hospital Clínico San Carlos, Madrid, Spain
c Unidad de Reumatología, Hospital Universitario Marqués de Valdecilla, Santander, Spain
d Servicio de Reumatología, Hospital Clínico Universitario San Carlos, Madrid, Spain
e Unidad de Espondiloartropatías, Hospital de la Vall d’Hebron, Barcelona, Spain
f Departamento de Gestión Sanitaria y Relaciones Institucionales, AbbVie Farmacéutica, S.L.U., Madrid Spain
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Tables (5)
Table 1. Incidence, Overall Costs and Cost per Patient According to the Type of Noninfectious Uveitis in Spain in 2011.
Table 2. Number of Cases and Distribution According to Gender, Age and Type of Noninfectious Uveitis in Spain in 2011.
Table 3. Use of Resources and Total Costs of Noninfectious Uveitis in Spain in 2011.
Table 4. Total Costs (in Thousands of €) per Type of Noninfectious Uveitis in Spain in 2011.
Table 5. Costs (€) and Resources Used per Patient According to Type of Noninfectious Uveitis in Spain in 2011.
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Abstract
Objectives

There is no updated information on epidemiology and cost of management of non infectious uveitis (NIU) in Spain. This study assessed the frequency of various types of uveítis as well as associated costs of resources used in their management.

Material and method

NIU epidemiological data and direct costs were collected from a literature search. This was complemented with consensus information from 2 expert panel meetings and data from questionnaires to ophthalmologists and rheumatologists, experts on these conditions. Healthcare resources costs were obtained from the Oblikue database, from a medical society and from approved drug prices in Spain.

Results

During 2011 the estimate number of NIU was 9398 (45% male, 70% aged 16–65 years). Incidence per type of uveitis was: acute anterior uveitis (AAU) 55%; posterior uveitis (PU) and pan-uveitis (PanU) 15% each; adult chronic anterior uveitis, pediatric chronic anterior uveitis and intermediate uveitis 5% each. Among total costs (77,834,282.10€), initial drug therapy was the highest (43,602,359.29€), followed by surgical treatment of complications (8,367,420.43€). With respect to types of uveitis, PanU (26,692,948.29€), PU (22,283,330.50€) and AAU (14,336,755.38€) showed the highest associated costs.

Conclusions

Non infectious uveitis is associated to high costs in Spain, both in its diagnosis and in its treatment. Early diagnosis and treatment should allow for substantial savings for the National Health System.

Keywords:
Uveitis
Direct costs of disease
Spain
Resumen
Objetivos

No existen datos actualizados sobre la epidemiología y los costes asociados de la uveítis no infecciosa (UNI) en España. Este estudio investiga la frecuencia de los tipos de uveítis y el coste de los recursos utilizados en su manejo en 2011.

Material y método

Se recogió información mediante búsqueda bibliográfica de datos epidemiológicos y de costes directos de la UNI. La información se completó mediante consenso de 2 paneles de expertos y cuestionario a oftalmólogos y reumatólogos especialistas en esta enfermedad. Los costes de los recursos se obtuvieron de la base de datos Oblikue, de una sociedad médica y de los precios de los medicamentos aprobados en España.

Resultados

En 2011 se diagnosticaron 9.398 nuevos pacientes de UNI (45% hombres, el 70% entre 16 y 65 años). La incidencia por tipos fue: uveítis anterior aguda (UAA) 55%, uveítis posterior (UP) y panuveítis (PU) 15% y uveítis anterior crónica en edad adulta, uveítis anterior crónica pediátrica y uveítis intermedia 5%. Del total de costes calculados (77.834.282,10€), el tratamiento farmacológico inicial fue el recurso más costoso (43.602.359,29€), seguido del tratamiento quirúrgico de las complicaciones (8.367.420,43€). Respecto a los tipos de uveítis, los costes asociados más elevados fueron los de la PU (26.692.948,29€), la UP (22.283.330,50€) y la UAA (14.336.755,38€).

Conclusiones

La UNI en España genera unos elevados costes tanto de diagnóstico como de tratamiento. Un diagnóstico y tratamiento precoz de la enfermedad permitirían un ahorro sustancial al Sistema Nacional de Salud.

Palabras clave:
Uveítis
Coste directo de la enfermedad
España

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