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Vol. 8. Issue 2.
Pages 93-97 (March - April 2012)
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Vol. 8. Issue 2.
Pages 93-97 (March - April 2012)
Continuing medical education
DOI: 10.1016/j.reumae.2011.05.005
Premenopausal Osteoporosis: How to Treat?
Osteoporosis premenopáusica: ¿cómo tratarla?
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Melania Martínez-Morillo
Corresponding author
melaniamm@gmail.com

Corresponding author.
, Dolors Grados, Susana Holgado
Sección de Reumatología, Hospital Universitario Germans Trias i Pujol, Barcelona, Spain
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Table 1. Causes of Secondary Osteoporosis in Premenopausal Women.
Abstract

There is no agreement in defining osteoporosis in premenopausal women and diagnosis must be done carefully and not based on densitometric parameters. One must take into account the presence of other risk factors and history of fragility fractures, diseases or drugs that cause bone loss. Over 50% of premenopausal women with osteoporosis will have a secondary cause, with the remainder diagnosed with idiopathic osteoporosis. Therapeutic considerations are limited by a few studies in this group of patients, especially in regard to the risk of fractures. On the other hand, the FRAX index cannot be applied to premenopausal women. This article will review the measures to apply depending on the type of premenopausal osteoporosis, based on current scientific evidence.

Keywords:
Osteoporosis
Premenopausal
Treatment
Young
Resumen

No existe un acuerdo para definir la osteoporosis en mujeres premenopáusicas y el diagnóstico debe realizarse cuidadosamente y sin basarse únicamente en parámetros densitométricos. Hay que tener en cuenta la presencia de otros factores de riesgo como los antecedentes de fracturas por fragilidad, enfermedades o fármacos osteopenizantes. Más del 50% de las mujeres con osteoporosis premenopáusica van a presentar una causa secundaria, el resto serán diagnosticadas de osteoporosis idiopática. Las consideraciones terapéuticas están limitadas por los escasos estudios en este grupo de pacientes, sobre todo en lo que se refiere al riesgo de fracturas. Por otro lado, no disponemos del índice de FRAX, ya que no se puede aplicar a pacientes premenopáusicas. Este artículo pretende realizar una revisión sobre la actitud que se debe seguir según el tipo de osteoporosis premenopáusica basándonos en la evidencia científica actual.

Palabras clave:
Osteoporosis
Menopausia
Tratamiento
Joven

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