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Vol. 9. Issue 4.
Pages 246-247 (July - August 2013)
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Vol. 9. Issue 4.
Pages 246-247 (July - August 2013)
Case report
DOI: 10.1016/j.reumae.2012.01.002
Sweet Syndrome Associated With Myelodysplastic Syndrome: Report of a Case. Review of the Literature
Síndrome de Sweet asociado a síndrome mielodisplásico: a propósito de un caso. Revisión de la literatura
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Delia Reinaa,??
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deliareinasanz@gmail.com

Corresponding author.
, Dacia Cerdàa, Daniel Roiga, Ramon Fígulsa, M. Luz Villegasb, Hèctor Corominasa
a Unidad de Reumatología, Hospital Sant Joan Despí Moisès Broggi, Sant Joan Despí, Barcelona, Spain
b Servicio de Medicina Interna, Hospital General de l’Hospitalet, Barcelona, Spain
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Abstract

Sweet's syndrome or acute neutrophilic febrile dermatosis is a systemic disease of unknown etiology characterized by the appearance of skin lesions produced by a neutrophilic dermal infiltrate, fever, and peripheral leukocytosis. It may be associated with hematologic diseases, including leukemia, with immune diseases as rheumatoid arthritis, or can occur in isolation. The myelodysplasias are hematological disorders characterized by one or more cytopenias secondary to bone marrow dysfunction. We present the case of a patient with Sweet's syndrome associated with myelodysplastic syndrome and treated with glucocorticoids who did not present a good clinical outcome. We discuss the different treatment of these diseases because in most cases glucocorticoids, which are the treatment of choice in Sweet's syndrome, may be insufficient.

Keywords:
Sweet syndrome
Myelodysplastic syndrome
Arthritis
Resumen

El síndrome de Sweet o dermatosis neutrofílica febril aguda es una enfermedad sistémica de etiología desconocida, caracterizada por la aparición de lesiones cutáneas producidas por un infiltrado dérmico neutrofílico, fiebre y leucocitosis periférica. Puede estar asociado a enfermedades hematológicas, incluida la leucemia, inmunológicas como la artritis reumatoide o presentarse de forma aislada. Las mielodisplasias son trastornos hematológicos caracterizados por una o más citopenias secundarias a la disfunción de la médula ósea. Se presenta el caso de un paciente con síndrome de Sweet asociado a un síndrome mielodisplásico que ha seguido tratamiento con glucocorticoides y no ha presentado una buena evolución clínica. Se discuten los diferentes tratamientos de estas enfermedades porque en la mayoría de las ocasiones los glucocorticoides, que son el tratamiento de elección en el síndrome de Sweet, pueden ser insuficientes.

Palabras clave:
Síndrome de Sweet
Síndrome mielodisplásico
Artritis

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