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        "titulo" => "&#191;Los estilos de humor predicen la respuesta cl&#237;nica al programa MINDSET &#40;MINDfulneSs &#38; EducaTion&#41;&#63; Un estudio piloto en pacientes con fibromialgia"
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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Fibromyalgia &#40;FM&#41; is a disabling syndrome characterized by chronic widespread pain along with fatigue&#44; stiffness&#44; sleep problems&#44; psychological distress and cognitive disturbances&#46;<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">1</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">The importance of emotion regulation strategies to face chronic pain has been highlighted in previous studies as they are related to symptomatology and impact of the disease&#46;<a class="elsevierStyleCrossRef" href="#bib0095"><span class="elsevierStyleSup">2</span></a> Humor has been considered an effective coping strategy&#59; the humor styles described by Martin&#44; Puhlik-Doris&#44; Larsen&#44; Gray&#44; and Weir&#44;<a class="elsevierStyleCrossRef" href="#bib0100"><span class="elsevierStyleSup">3</span></a> which are divided into positive &#40;<span class="elsevierStyleItalic">affiliative</span> and <span class="elsevierStyleItalic">self-enhancing</span>&#41; and negative &#40;<span class="elsevierStyleItalic">self-defeating</span> and <span class="elsevierStyleItalic">aggressive</span>&#41;&#44; have been observed to correlate significantly and in the expected direction with self-esteem&#44; positive emotions&#44; optimism&#44; hostility&#44; and psychological distress&#44; among other variables in patients with different pathologies&#46; In chronic pain conditions&#44; there is promising evidence that humor may help in dealing with its related emotional distress&#46;<a class="elsevierStyleCrossRef" href="#bib0105"><span class="elsevierStyleSup">4</span></a> In the case of FM&#44; some studies have found that the use of humor was associated with reduced anxiety&#44; psychological distress&#44; and symptoms&#44; and with increased ability to control pain and positive reappraisal&#46;<a class="elsevierStyleCrossRef" href="#bib0110"><span class="elsevierStyleSup">5</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">Humor has been described as similar to the <span class="elsevierStyleItalic">decentering</span> construct&#44;<a class="elsevierStyleCrossRef" href="#bib0115"><span class="elsevierStyleSup">6</span></a> which is the ability to &#8220;step back&#8221; mentally from a situation to become more fully aware of it&#44; as well as finding alternate ways of interpreting and responding effectively to a given situation&#46; In this regard&#44; some styles of humor may enhance a more flexible psychological response&#59; it is said&#44; a change in perspective to not become fused with mental contents &#40;e&#46;g&#46; negative thoughts&#41; which may enable a more regulated emotional response&#46; Coherently&#44; positive correlations between positive humor styles and mindfulness trait has been previously reported&#44;<a class="elsevierStyleCrossRef" href="#bib0120"><span class="elsevierStyleSup">7</span></a> and both coping and mindfulness variables have been found to be moderators of the clinical response to different psychotherapies&#44; including mindfulness-based interventions&#46;<a class="elsevierStyleCrossRef" href="#bib0125"><span class="elsevierStyleSup">8</span></a> Mindfulness facets have been observed to be significantly related to FM impact&#44; with higher impact being associated with lower mindfulness levels except for <span class="elsevierStyleItalic">Observing</span> facet&#44; which was positively related&#59; this association suggests that&#44; in FM&#44; this mindfulness facet would be more related to pain amplification rather than mindful observation&#46;<a class="elsevierStyleCrossRef" href="#bib0130"><span class="elsevierStyleSup">9</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">The present pilot study aimed to examine the predictive effect of humor styles on perceived clinical changes and functional impact after the multicomponent intervention named MINDSET &#40;MINDfulneSs and EducaTion&#41; in a sample of FM patients&#46; In addition&#44; the study explored for the first time the association between humor styles&#44; mindfulness&#44; and the functional impact of FM&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Methods</span><p id="par0025" class="elsevierStylePara elsevierViewall">Thirty-five patients from the EUDAIMON project &#40;see Feliu-Soler et al&#46;&#44; 2016 for the study protocol&#41;<a class="elsevierStyleCrossRef" href="#bib0135"><span class="elsevierStyleSup">10</span></a> participated in the current study&#44; which was performed following the ethical standards laid down in the 1964 Declaration of Helsinki and its subsequent updates&#46; The EUDAIMON project was approved by the Ethics Committee at the Sant Joan de D&#233;u Foundation &#40;PIC-102-15&#41; and all patients signed the informed consent&#46; These patients were offered to participate in the present study as a compensation for being allocated to the passive control arm &#40;usual care&#41; in EUDAIMON&#46; All the participants in this study presented FM according to the American College of Rheumatology 1990 criteria&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">The Spanish-validated version of the following questionnaires was administered during the study&#44; next to a socio-demographic questionnaire&#58;<ul class="elsevierStyleList" id="lis0005"><li class="elsevierStyleListItem" id="lsti0005"><span class="elsevierStyleLabel">-</span><p id="par0035" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Humor Styles Questionnaire</span> &#40;HSQ&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0100"><span class="elsevierStyleSup">3</span></a> It is a 32-item questionnaire that assesses the individual&#39;s tendency to experience or use four different humor styles&#58; <span class="elsevierStyleItalic">affiliative</span>&#44; <span class="elsevierStyleItalic">self-enhancing</span>&#44; <span class="elsevierStyleItalic">self-defeating</span>&#44; and <span class="elsevierStyleItalic">aggressive</span>&#46; This questionnaire was administered before the intervention&#46;</p></li><li class="elsevierStyleListItem" id="lsti0010"><span class="elsevierStyleLabel">-</span><p id="par0040" class="elsevierStylePara elsevierViewall">The 15-item version of the <span class="elsevierStyleItalic">Five-Facets Mindfulness Questionnaire</span> &#40;FFMQ-15&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0140"><span class="elsevierStyleSup">11</span></a> This is a short version of the original FFMQ &#40;with 39 items&#41; that evaluates five facets of mindfulness&#58; <span class="elsevierStyleItalic">Observing</span>&#44; <span class="elsevierStyleItalic">Describing</span>&#44; <span class="elsevierStyleItalic">Acting with awareness</span>&#44; <span class="elsevierStyleItalic">Non-judging</span> and <span class="elsevierStyleItalic">Non-reacting</span>&#46; This questionnaire was administered before the intervention&#46;</p></li><li class="elsevierStyleListItem" id="lsti0015"><span class="elsevierStyleLabel">-</span><p id="par0045" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Patient Global Impression of Change</span> &#40;PGIC&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0145"><span class="elsevierStyleSup">12</span></a> It is a brief scale &#40;6 items&#41; that assesses the individual&#39;s perceived global change and the specific improvement in different areas&#58; physical and social functioning&#44; work-related activities&#44; mood and pain&#46; This questionnaire was administered after the intervention&#46;</p></li><li class="elsevierStyleListItem" id="lsti0020"><span class="elsevierStyleLabel">-</span><p id="par0050" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Revised Fibromyalgia Impact Questionnaire</span> &#40;FIQR&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0150"><span class="elsevierStyleSup">13</span></a> This is considered the &#8220;gold standard&#8221; for assessing functional impact in FM patients&#59; it consists of 21 items that evaluate three domains&#58; physical dysfunction&#44; overall impact&#44; and symptomatology&#46; The FIQR was administered both before and after the intervention&#46;</p></li></ul></p><p id="par0055" class="elsevierStylePara elsevierViewall">The MINDSET intervention consisted of four sessions psychoeducation about the FM&#44; based on a previously validated program&#44;<a class="elsevierStyleCrossRef" href="#bib0155"><span class="elsevierStyleSup">14</span></a> and four sessions of mindfulness training&#44; based on the Mindfulness-Based Stress Reduction curriculum&#46;<a class="elsevierStyleCrossRef" href="#bib0160"><span class="elsevierStyleSup">15</span></a> The sessions&#44; which lasted about 2<span class="elsevierStyleHsp" style=""></span>h and were conducted twice per week&#44; were run by health psychologists in a group setting of 8&#8211;10 patients per group&#46; The main targets of the intervention were&#58; increase knowledge about FM&#44; promotion of healthy habits&#44; and fostering emotion regulation in face of adversity&#46; This intervention was an add-on to the patient&#39;s usual care &#40;usually&#44; medication&#41;&#46; No additional active treatments were provided&#46; <a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a> presents a summary of the sessions&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0060" class="elsevierStylePara elsevierViewall">SPSS v22 was used for all statistical analyses&#46; A positive&#47;negative humor styles ratio was calculated to provide an index indicative of proportion of use of both types of humor styles&#46; A linear regression &#40;with step-wise method&#41; was used to analyze the predictive effect of humor styles on the perceived clinical change after the intervention&#46; A linear hierarchic regression was computed to assess the unique effect of humor styles after controlling by mindfulness scores&#46; Spearman correlations were performed to evaluate associations between humor styles and clinical and mindfulness variables at baseline&#46; Wilcoxon&#39;s test was then computed to analyze pre-post differences and Hedges&#8217; <span class="elsevierStyleItalic">g</span> was used to calculate the effect size&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Results</span><p id="par0065" class="elsevierStylePara elsevierViewall"><a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a> presents the baseline data of the sample&#46; Change in FIQR scores &#40;i&#46;e&#46;&#44; functional impact of the FM&#41; was not predicted by any humor style&#44; but significant effects were found for the PGIC &#40;i&#46;e&#46;&#44; perceived clinical change&#41;&#46; In the case of perceived change in physical activity&#44; <span class="elsevierStyleItalic">affiliative humor</span> emerged as a significant predictor &#40;<span class="elsevierStyleItalic">&#946;</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#8722;0&#46;395&#44; <span class="elsevierStyleItalic">F</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>4&#46;44&#44; <span class="elsevierStyleItalic">R</span><span class="elsevierStyleSup">2</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;156&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;046&#41;&#59; on the other hand&#44; the positive&#47;negative humor style ratio was a significant predictor of perceived change in work activity &#40;<span class="elsevierStyleItalic">&#946;</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#8722;0&#46;432&#44; <span class="elsevierStyleItalic">F</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>5&#46;51&#44; <span class="elsevierStyleItalic">R</span><span class="elsevierStyleSup">2</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;187&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;027&#41;&#44; mood &#40;<span class="elsevierStyleItalic">&#946;</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#8722;0&#46;454&#44; <span class="elsevierStyleItalic">F</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>6&#46;22&#44; <span class="elsevierStyleItalic">R</span><span class="elsevierStyleSup">2</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;206&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;020&#41;&#44; and pain &#40;<span class="elsevierStyleItalic">&#946;</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#8722;0&#46;498&#44; <span class="elsevierStyleItalic">F</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>7&#46;90&#44; <span class="elsevierStyleItalic">R</span><span class="elsevierStyleSup">2</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;248&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;010&#41;&#46; In addition&#44; <span class="elsevierStyleItalic">self-defeating</span><span class="elsevierStyleItalic">humor</span> significantly predicted the perceived change in pain &#40;<span class="elsevierStyleItalic">&#946;</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;467&#44; <span class="elsevierStyleItalic">F</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>6&#46;68&#44; <span class="elsevierStyleItalic">R</span><span class="elsevierStyleSup">2</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;218&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;016&#41;&#46; All these effects were preserved after controlling for the mindfulness-facets&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0070" class="elsevierStylePara elsevierViewall">Some significant correlations were found between humor styles&#44; FIQR and mindfulness facets&#46; The <span class="elsevierStyleItalic">affiliative</span> style presented significant negative correlations with FIQR scores &#40;<span class="elsevierStyleItalic">r</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#8722;&#46;50&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;004&#41;&#46; No significant correlations were found with any of the mindfulness facets&#46; The <span class="elsevierStyleItalic">self-enhancing</span> style presented a significant correlation with the FIQR symptoms subscale &#40;<span class="elsevierStyleItalic">r</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#8722;&#46;38&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;033&#41;&#44; and with the mindfulness facets <span class="elsevierStyleItalic">Describing</span> &#40;<span class="elsevierStyleItalic">r</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;50&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;003&#41;&#44; <span class="elsevierStyleItalic">Acting with awareness</span> &#40;<span class="elsevierStyleItalic">r</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;37&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;039&#41;&#44; and <span class="elsevierStyleItalic">Non-judging</span> &#40;<span class="elsevierStyleItalic">r</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;38&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;033&#41;&#46; The <span class="elsevierStyleItalic">aggressive</span> style correlated positively and significantly with the total FIQR score &#40;<span class="elsevierStyleItalic">r</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;41&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;021&#41;&#44; and with the mindfulness facet <span class="elsevierStyleItalic">Non-judging</span> &#40;<span class="elsevierStyleItalic">r</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#8722;&#46;44&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;012&#41;&#46; On the other hand&#44; <span class="elsevierStyleItalic">self-defeating</span> humor did not correlate significantly with the FIQR nor with the FFMQ-15&#46; Finally&#44; when considering the humor styles ratio&#44; significant correlations were found for the FIQR &#40;<span class="elsevierStyleItalic">r</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#8722;&#46;54&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;002&#41; and&#44; regarding mindfulness facets&#44; with <span class="elsevierStyleItalic">Acting with awareness</span> &#40;<span class="elsevierStyleItalic">r</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;36&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;042&#41; and with <span class="elsevierStyleItalic">Non-judging</span> &#40;<span class="elsevierStyleItalic">r</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;58&#44; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;001&#41;&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">Finally&#44; and despite not being the main aim of this study&#44; it needs to be noticed that the intervention achieved a notable degree of adherence &#40;74&#37; of attendance to the sessions&#41; and was considered satisfactory &#40;9&#47;10&#41;&#44; useful &#40;8&#46;9&#47;10&#41;&#44; recommendable &#40;8&#46;7&#41; and non-aversive &#40;0&#46;5&#47;10&#41; by the participants in a post-treatment ad-hoc opinion survey&#46; After the intervention&#44; the mean FIQR score showed a significant 14&#37; of improvement &#40;<span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;001&#41;&#44; although the effect size was small &#40;Hedges&#8217; <span class="elsevierStyleItalic">g</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;36&#41;&#46; In the case of perceived changes after the treatment &#40;PGIC&#59; 1<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>much better&#44; 4<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>no change&#44; 7<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>much worse&#41;&#44; overall small improvements were observed&#58; mood &#40;M<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>2&#46;72&#44; SD<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1&#46;31&#41;&#44; social activity &#40;M<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>2&#46;93&#44; SD<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1&#46;13&#41;&#44; overall status &#40;M<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>3&#46;14&#44; SD<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;83&#41;&#44; physical activity &#40;M<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>3&#46;38&#44; SD<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;86&#41;&#44; work activity &#40;M<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>3&#46;41&#44; SD<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1&#46;05&#41;&#44; and pain &#40;M<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>3&#46;59&#44; SD<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;91&#41;&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Discussion</span><p id="par0080" class="elsevierStylePara elsevierViewall">To date&#44; this is the first study to assess the predictive role of humor styles in the perceived clinical changes of a mindfulness-based intervention for FM&#46; Our analyses indicate some predictive effects for <span class="elsevierStyleItalic">affiliative humor</span>&#44; <span class="elsevierStyleItalic">self-defeating humor</span>&#44; and the ratio on different areas of the perceived clinical improvement&#46; A possible explanation could be that those patients who scored higher in positive humor styles would probably present certain personality traits &#40;e&#46;g&#46; openness to experience&#44; psychological flexibility&#44; self-efficacy&#44; see Martin et al&#46;<a class="elsevierStyleCrossRef" href="#bib0100"><span class="elsevierStyleSup">3</span></a>&#41; which could facilitate to act on the suggestions and advice given during the sessions&#44; such as practicing aerobic exercise&#59; on the other hand&#44; patients with higher levels of negative humor styles could also present higher levels of depressive symptomatology&#44; lower self-efficacy and more external locus of control&#44;<a class="elsevierStyleCrossRef" href="#bib0165"><span class="elsevierStyleSup">16</span></a> which could hinder learning and implementing the practices addressed to reduce pain and its consequences&#46; Therefore&#44; an interesting challenge would be finding ways to increase the ratio of humor styles&#44; particularly in those cases in which the ratio is lower than 1&#58;1 &#40;i&#46;e&#46;&#44; more frequent use of negative styles&#41;&#46; Future studies could focus on testing interventions addressed to increasing this ratio and testing the clinical implications&#46;</p><p id="par0085" class="elsevierStylePara elsevierViewall">To our knowledge&#44; the present pilot study is also the first to use the FFMQ to study the relationship between mindfulness and humor styles&#59; our results indicate that <span class="elsevierStyleItalic">self-enhancing humor</span> is the most strongly mindfulness-related humor style&#44; as it has been significantly associated with multiple facets&#46; It is possible that these associations may be related to the ability to regulate emotions and accept negative emotional states that cannot be immediately changed&#46;<a class="elsevierStyleCrossRef" href="#bib0115"><span class="elsevierStyleSup">6</span></a> On the other hand&#44; <span class="elsevierStyleItalic">aggressive humor</span> presented a significant negative correlation with <span class="elsevierStyleItalic">Non-judging</span>&#44; which is defined as refraining from judgments or self-criticism about having certain experiences &#40;e&#46;g&#46;&#44; feeling anxious&#41;&#46;</p><p id="par0090" class="elsevierStylePara elsevierViewall">Some limitations of the present study cannot be overlooked&#58; the small number of patients and the absence of a control group hampered analyses and reduced the robustness of the results&#46; The lack of other clinical&#44; coping-related and mindfulness measures administered both at pre- and at post-intervention limited the soundness of the conclusions&#44; which in most cases have an important hypothetical base&#46; Future studies should also evaluate other aspects of humor such as humor production or appreciation&#44; and these studies should be conducted considering the socio-cultural differences regarding humor that some studies have already assessed&#46;<a class="elsevierStyleCrossRef" href="#bib0170"><span class="elsevierStyleSup">17</span></a></p><p id="par0095" class="elsevierStylePara elsevierViewall">In conclusion&#44; the preliminary findings of this pilot study indicate that <span class="elsevierStyleItalic">affiliative humor</span> and the ratio of humor styles seem to be predictors of self-reported changes after the MINDEST intervention in different areas which are relevant for FM patients &#40;e&#46;g&#46;&#44; pain&#44; work&#44; mood&#41;&#46; These effects could be attributed to a better disposition in patients with positive humor styles to learn and implement the concepts and resources that the intervention offered&#46; Also&#44; the <span class="elsevierStyleItalic">self-enhancing humor</span> appeared to be related to a number of mindfulness facets&#46; Despite the considerable limitations of this study&#44; these preliminary results contribute to knowledge on the link between humor and chronic pain and suggest some lines of research which could be undertaken in future studies&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Funding</span><p id="par0100" class="elsevierStylePara elsevierViewall">The study has been funded in part by the Instituto de Salud Carlos III &#40;ISCIII&#41;&#44; Ministry of Economy and Competitiveness &#40;Spain&#41; through the Network for Prevention and Health Promotion in Primary Care &#40;RD16&#47;0007&#47;0012&#41;&#44; by a grant for research projects in health from ISCIII &#40;PI15&#47;00383&#41; co-financed with <span class="elsevierStyleGrantSponsor" id="gs1">European Union ERDF</span> funds&#46; The first listed author has a FI predoctoral contract awarded by the Agency for Management of University and Research Grants &#40;AGAUR&#59; 2017&#59; FI&#95;B00754&#41;&#46; The third listed author has a &#8220;Sara Borrell&#8221; research contract from the ISCIII &#40;CD16&#47;00147&#41;&#46; The fourth listed author has a FI predoctoral contract awarded by the Agency for Management of University and Research Grants &#40;AGAUR&#59; 2018&#59; FI&#95;B00783&#41;&#46; The last listed author &#40;JVL&#41; has a &#8220;Miguel Servet&#8221; research contract from the ISCIII &#40;CP14&#47;00087&#41;&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Conflict of interest</span><p id="par0105" class="elsevierStylePara elsevierViewall">The authors declare no conflicts of interest&#46;</p></span></span>"
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            0 => "Humor styles"
            1 => "Humor Styles Questionnaire"
            2 => "Fibromyalgia"
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            0 => "Estilos de humor"
            1 => "<span class="elsevierStyleItalic">Humor Styles Questionnaire</span>"
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            3 => "<span class="elsevierStyleItalic">Fibromyalgia Impact Questionnaire Revised</span>"
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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Background and aim</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Humor has been described as an effective coping strategy for dealing with chronic pain conditions&#59; likewise&#44; coping strategies predict some clinical outcomes after cognitive-behavioral therapy and mindfulness-based interventions&#46; The present study aims to preliminarily explore the role of humor styles in predicting clinical changes after the multicomponent intervention &#40;MINDSET&#41; that combines mindfulness and psychoeducation for fibromyalgia &#40;FM&#41; patients&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Material and methods</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">A subsample of 35 patients with FM of the EUDAIMON study&#44; a randomized controlled trial&#44; was used for the present study&#59; linear regressions and Spearman&#39;s correlations were computed&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleItalic">Affiliative</span> humor and positive&#47;negative ratio humor styles had a unique predictive effect on self-reported clinical changes&#46; Significant correlations between humor styles with functional impact and mindfulness facets were observed&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusions</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Some humor styles may imply a better disposition in patients to learn and implement the concepts and resources that the intervention offered&#46;</p></span>"
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      "es" => array:3 [
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        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Antecedentes y objetivo</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">El humor se considera una estrategia de afrontamiento efectiva para afrontar enfermedades cr&#243;nicas&#59; asimismo&#44; las estrategias de afrontamiento pueden predecir cambios cl&#237;nicos experimentados tras intervenciones cognitivo-conductuales y basadas en <span class="elsevierStyleItalic">mindfulness</span>&#46; El presente estudio explora el rol de los estilos de humor en la predicci&#243;n de cambios cl&#237;nicos tras una intervenci&#243;n multicomponente &#40;MINDSET&#44; <span class="elsevierStyleItalic">mindfulness</span><span class="elsevierStyleHsp" style=""></span>&#43;<span class="elsevierStyleHsp" style=""></span>psicoeducaci&#243;n&#41; para pacientes con fibromialgia&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Materiales y m&#233;todos</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">En este estudio participaron 35 pacientes con fibromialgia&#44; una submuestra del ensayo controlado y aleatorizado del estudio EUDAIMON&#46; Se realizaron regresiones lineales y correlaciones de Spearman&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">El humor <span class="elsevierStyleItalic">afiliativo</span> y la ratio de estilos positivos&#47;negativos mostraron un efecto predictor en cambios cl&#237;nicos auto-reportados&#46; Se observaron correlaciones significativas entre estilos de humor&#44; impacto funcional y facetas de <span class="elsevierStyleItalic">mindfulness</span>&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclusiones</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Algunos estilos de humor pueden implicar una mejor predisposici&#243;n en los pacientes para aprender y aplicar los recursos que la intervenci&#243;n ofrece&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0025"
            "titulo" => "Antecedentes y objetivo"
          ]
          1 => array:2 [
            "identificador" => "abst0030"
            "titulo" => "Materiales y m&#233;todos"
          ]
          2 => array:2 [
            "identificador" => "abst0035"
            "titulo" => "Resultados"
          ]
          3 => array:2 [
            "identificador" => "abst0040"
            "titulo" => "Conclusiones"
          ]
        ]
      ]
    ]
    "multimedia" => array:2 [
      0 => array:8 [
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        "etiqueta" => "Table 1"
        "tipo" => "MULTIMEDIATABLA"
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            "identificador" => "at1"
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        "tabla" => array:1 [
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            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Session&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Type&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Content&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Education&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Introduction of the course&#46; Overview of what we know about FM&#44; diagnosis&#44; causes&#44; symptoms and treatment&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Mindfulness&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Introduction to mindfulness and its relation to chronic pain&#46; Mindful eating &#40;raisin exercise&#41;&#44; body scan meditation&#44; mindfulness in daily activities&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Education&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Myths about fibromyalgia and tips for maintaining the pillars of good health&#58; rest&#44; healthy diet&#44; exercise practice&#44; not consumption of tobacco&#47;drugs&#44; moderate intake of caffeine&#47;alcohol&#44; and follow doctors&#8217; prescriptions&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Mindfulness&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Introduction to the 3-min pause exercise&#44; focus on the breath&#44; situation&#8211;thoughts&#8211;emotions relationship&#44; thoughts vs&#46; facts&#44; interpretation vs&#46; observation&#44; awareness of pleasant experiences&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Education&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Discussion of the most frequent emotions that patients with FM must deal with&#46; Tips for emotion management and communication skills&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Mindfulness&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Three-minute pause exercise in the face of adversity&#44; mindfulness of difficult emotions&#44; reacting vs&#46; responding&#44; walking meditation&#44; choosing to be present&#44; awareness of unpleasant experiences&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Education&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">What services and resources do FM patients have&#63; Health care system&#44; communitarian system&#44; and summary of the course&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Mindfulness&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Sitting meditation&#44; action plan&#44; walking meditation&#44; everyday mindfulness&#44; and additional resources to continue practicing&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
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        "descripcion" => array:1 [
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      1 => array:8 [
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        "etiqueta" => "Table 2"
        "tipo" => "MULTIMEDIATABLA"
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            "identificador" => "at2"
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          "leyenda" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleItalic">Note</span>&#58; FIQR&#58; Fibromyalgia Impact Questionnaire &#8211; Revised&#59; HSQ&#58; Humor Styles Questionnaire&#59; FFMQ-15&#58; Five Facets Mindfulness Questionnaire &#8211; 15 item version&#59; one patient did not attend to the first session&#59; thus&#44; the table presents data for 34 patients except for sex&#44; age&#44; and years of diagnosis&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Patients with FM &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>35&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="2" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Sociodemographic outcomes</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Sex&#44; no&#46; females &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">34 &#40;97&#46;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Age&#44; mean &#40;SD&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">54&#46;97 &#40;8&#46;65&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Years of diagnosis&#44; mean &#40;SD&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#46;71 &#40;6&#46;47&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="2" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="2" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Marital status&#44; n &#40;&#37;&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Married&#47;living with a partner&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">28 &#40;82&#46;4&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Separated&#47;divorced&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5 &#40;14&#46;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Widowed&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1 &#40;2&#46;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="2" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="2" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Living arrangement&#44; n &#40;&#37;&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Living alone&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2 &#40;5&#46;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Living with partner&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">32 &#40;94&#46;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="2" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="2" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Education level&#44; n &#40;&#37;&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Illiterate&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1 &#40;2&#46;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Did not graduate from primary school&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2 &#40;5&#46;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Primary school&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">13 &#40;38&#46;2&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Secondary school&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">17 &#40;50&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>University&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1 &#40;2&#46;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="2" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="2" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Employment status&#44; n &#40;&#37;&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Homemaker&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3 &#40;8&#46;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Paid employment&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">9 &#40;26&#46;5&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Paid employment but in sick leave&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2 &#40;5&#46;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Unemployed with subsidy&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5 &#40;14&#46;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Unemployed without subsidy&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5 &#40;14&#46;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Retired&#47;pensioner&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5 &#40;14&#46;7&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Temporal disability&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1 &#40;2&#46;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Others&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4 &#40;11&#46;8&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="2" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="2" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Clinical severity&#44; humor styles and mindfulness</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>FIQR &#8211; Total score&#44; mean &#40;SD&#41; &#40;0&#8211;100&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">58&#46;11 &#40;22&#46;25&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Physical impairment &#40;0&#8211;30&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">17&#46;41 &#40;7&#46;31&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Overall impact &#40;0&#8211;20&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#46;70 &#40;6&#46;79&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Symptoms &#40;0&#8211;50&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">34 &#40;10&#46;42&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="2" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="2" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">HSQ&#44; mean &#40;SD&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Affiliative humor &#40;8&#8211;56&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">36&#46;62 &#40;6&#46;67&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Self-enhancing humor &#40;8&#8211;56&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">34&#46;04 &#40;9&#46;68&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Self-defeating humor &#40;8&#8211;56&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">20&#46;64 &#40;7&#46;52&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Aggressive humor &#40;8&#8211;56&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">18&#46;87 &#40;7&#46;41&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="2" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="2" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">FFMQ-15&#44; mean &#40;SD&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Observing &#40;5&#8211;15&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#46;94 &#40;2&#46;92&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Describing &#40;5&#8211;15&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">9&#46;44 &#40;2&#46;70&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Acting with awareness &#40;5&#8211;15&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">10&#46;01 &#40;2&#46;86&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Non-reacting &#40;5&#8211;15&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#46;66 &#40;2&#46;61&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Non-judging &#40;5&#8211;15&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">10&#46;35 &#40;3&#46;68&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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                0 => "xTab2525135.png"
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          "en" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Baseline characteristics of the participants&#46;</p>"
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    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0015"
          "bibliografiaReferencia" => array:17 [
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3448
Vol. 17. Núm. 3.
Páginas 137-140 (marzo 2021)
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Do humor styles predict clinical response to the MINDSET (MINDfulneSs & EducaTion) program? A pilot study in patients with fibromyalgia
¿Los estilos de humor predicen la respuesta clínica al programa MINDSET (MINDfulneSs & EducaTion)? Un estudio piloto en pacientes con fibromialgia
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Adrián Pérez-Arandaa,b,
Autor para correspondencia
ap.aranda@pssjd.org

Corresponding author.
, Natalia Angarita-Osorioa,b,c, Albert Feliu-Solera,b, Laura Andrés-Rodrígueza,b,c, Xavier Borràsa,c, Juan V. Lucianoa,b
a Group of Psychological Research in Fibromyalgia & Chronic Pain (AGORA), Institut de Recerca Sant Joan de Déu, C/ Santa Rosa 39-57, 08950 Esplugues de Llobregat, Spain
b Teaching, Research & Innovation Unit, Parc Sanitari Sant Joan de Déu, Sant Boi de Llobregat, C/ Dr. Antoni Pujadas 42, 08830 Sant Boi de Llobregat, Spain
c Basic Psychology Unit, Universitat Autònoma de Barcelona, Barcelona, Spain
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Table 1. Content of the sessions.
Table 2. Baseline characteristics of the participants.
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Abstract
Background and aim

Humor has been described as an effective coping strategy for dealing with chronic pain conditions; likewise, coping strategies predict some clinical outcomes after cognitive-behavioral therapy and mindfulness-based interventions. The present study aims to preliminarily explore the role of humor styles in predicting clinical changes after the multicomponent intervention (MINDSET) that combines mindfulness and psychoeducation for fibromyalgia (FM) patients.

Material and methods

A subsample of 35 patients with FM of the EUDAIMON study, a randomized controlled trial, was used for the present study; linear regressions and Spearman's correlations were computed.

Results

Affiliative humor and positive/negative ratio humor styles had a unique predictive effect on self-reported clinical changes. Significant correlations between humor styles with functional impact and mindfulness facets were observed.

Conclusions

Some humor styles may imply a better disposition in patients to learn and implement the concepts and resources that the intervention offered.

Keywords:
Humor styles
Humor Styles Questionnaire
Fibromyalgia
Fibromyalgia Impact Questionnaire Revised
Mindfulness
Five Facets Mindfulness Questionnaire
Resumen
Antecedentes y objetivo

El humor se considera una estrategia de afrontamiento efectiva para afrontar enfermedades crónicas; asimismo, las estrategias de afrontamiento pueden predecir cambios clínicos experimentados tras intervenciones cognitivo-conductuales y basadas en mindfulness. El presente estudio explora el rol de los estilos de humor en la predicción de cambios clínicos tras una intervención multicomponente (MINDSET, mindfulness+psicoeducación) para pacientes con fibromialgia.

Materiales y métodos

En este estudio participaron 35 pacientes con fibromialgia, una submuestra del ensayo controlado y aleatorizado del estudio EUDAIMON. Se realizaron regresiones lineales y correlaciones de Spearman.

Resultados

El humor afiliativo y la ratio de estilos positivos/negativos mostraron un efecto predictor en cambios clínicos auto-reportados. Se observaron correlaciones significativas entre estilos de humor, impacto funcional y facetas de mindfulness.

Conclusiones

Algunos estilos de humor pueden implicar una mejor predisposición en los pacientes para aprender y aplicar los recursos que la intervención ofrece.

Palabras clave:
Estilos de humor
Humor Styles Questionnaire
Fibromialgia
Fibromyalgia Impact Questionnaire Revised
Mindfulness
Five Facets Mindfulness Questionnaire
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Introduction

Fibromyalgia (FM) is a disabling syndrome characterized by chronic widespread pain along with fatigue, stiffness, sleep problems, psychological distress and cognitive disturbances.1

The importance of emotion regulation strategies to face chronic pain has been highlighted in previous studies as they are related to symptomatology and impact of the disease.2 Humor has been considered an effective coping strategy; the humor styles described by Martin, Puhlik-Doris, Larsen, Gray, and Weir,3 which are divided into positive (affiliative and self-enhancing) and negative (self-defeating and aggressive), have been observed to correlate significantly and in the expected direction with self-esteem, positive emotions, optimism, hostility, and psychological distress, among other variables in patients with different pathologies. In chronic pain conditions, there is promising evidence that humor may help in dealing with its related emotional distress.4 In the case of FM, some studies have found that the use of humor was associated with reduced anxiety, psychological distress, and symptoms, and with increased ability to control pain and positive reappraisal.5

Humor has been described as similar to the decentering construct,6 which is the ability to “step back” mentally from a situation to become more fully aware of it, as well as finding alternate ways of interpreting and responding effectively to a given situation. In this regard, some styles of humor may enhance a more flexible psychological response; it is said, a change in perspective to not become fused with mental contents (e.g. negative thoughts) which may enable a more regulated emotional response. Coherently, positive correlations between positive humor styles and mindfulness trait has been previously reported,7 and both coping and mindfulness variables have been found to be moderators of the clinical response to different psychotherapies, including mindfulness-based interventions.8 Mindfulness facets have been observed to be significantly related to FM impact, with higher impact being associated with lower mindfulness levels except for Observing facet, which was positively related; this association suggests that, in FM, this mindfulness facet would be more related to pain amplification rather than mindful observation.9

The present pilot study aimed to examine the predictive effect of humor styles on perceived clinical changes and functional impact after the multicomponent intervention named MINDSET (MINDfulneSs and EducaTion) in a sample of FM patients. In addition, the study explored for the first time the association between humor styles, mindfulness, and the functional impact of FM.

Methods

Thirty-five patients from the EUDAIMON project (see Feliu-Soler et al., 2016 for the study protocol)10 participated in the current study, which was performed following the ethical standards laid down in the 1964 Declaration of Helsinki and its subsequent updates. The EUDAIMON project was approved by the Ethics Committee at the Sant Joan de Déu Foundation (PIC-102-15) and all patients signed the informed consent. These patients were offered to participate in the present study as a compensation for being allocated to the passive control arm (usual care) in EUDAIMON. All the participants in this study presented FM according to the American College of Rheumatology 1990 criteria.

The Spanish-validated version of the following questionnaires was administered during the study, next to a socio-demographic questionnaire:

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    Humor Styles Questionnaire (HSQ).3 It is a 32-item questionnaire that assesses the individual's tendency to experience or use four different humor styles: affiliative, self-enhancing, self-defeating, and aggressive. This questionnaire was administered before the intervention.

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    The 15-item version of the Five-Facets Mindfulness Questionnaire (FFMQ-15).11 This is a short version of the original FFMQ (with 39 items) that evaluates five facets of mindfulness: Observing, Describing, Acting with awareness, Non-judging and Non-reacting. This questionnaire was administered before the intervention.

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    Patient Global Impression of Change (PGIC).12 It is a brief scale (6 items) that assesses the individual's perceived global change and the specific improvement in different areas: physical and social functioning, work-related activities, mood and pain. This questionnaire was administered after the intervention.

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    Revised Fibromyalgia Impact Questionnaire (FIQR).13 This is considered the “gold standard” for assessing functional impact in FM patients; it consists of 21 items that evaluate three domains: physical dysfunction, overall impact, and symptomatology. The FIQR was administered both before and after the intervention.

The MINDSET intervention consisted of four sessions psychoeducation about the FM, based on a previously validated program,14 and four sessions of mindfulness training, based on the Mindfulness-Based Stress Reduction curriculum.15 The sessions, which lasted about 2h and were conducted twice per week, were run by health psychologists in a group setting of 8–10 patients per group. The main targets of the intervention were: increase knowledge about FM, promotion of healthy habits, and fostering emotion regulation in face of adversity. This intervention was an add-on to the patient's usual care (usually, medication). No additional active treatments were provided. Table 1 presents a summary of the sessions.

Table 1.

Content of the sessions.

Session  Type  Content 
Education  Introduction of the course. Overview of what we know about FM, diagnosis, causes, symptoms and treatment. 
Mindfulness  Introduction to mindfulness and its relation to chronic pain. Mindful eating (raisin exercise), body scan meditation, mindfulness in daily activities. 
Education  Myths about fibromyalgia and tips for maintaining the pillars of good health: rest, healthy diet, exercise practice, not consumption of tobacco/drugs, moderate intake of caffeine/alcohol, and follow doctors’ prescriptions. 
Mindfulness  Introduction to the 3-min pause exercise, focus on the breath, situation–thoughts–emotions relationship, thoughts vs. facts, interpretation vs. observation, awareness of pleasant experiences. 
Education  Discussion of the most frequent emotions that patients with FM must deal with. Tips for emotion management and communication skills. 
Mindfulness  Three-minute pause exercise in the face of adversity, mindfulness of difficult emotions, reacting vs. responding, walking meditation, choosing to be present, awareness of unpleasant experiences. 
Education  What services and resources do FM patients have? Health care system, communitarian system, and summary of the course. 
Mindfulness  Sitting meditation, action plan, walking meditation, everyday mindfulness, and additional resources to continue practicing. 

SPSS v22 was used for all statistical analyses. A positive/negative humor styles ratio was calculated to provide an index indicative of proportion of use of both types of humor styles. A linear regression (with step-wise method) was used to analyze the predictive effect of humor styles on the perceived clinical change after the intervention. A linear hierarchic regression was computed to assess the unique effect of humor styles after controlling by mindfulness scores. Spearman correlations were performed to evaluate associations between humor styles and clinical and mindfulness variables at baseline. Wilcoxon's test was then computed to analyze pre-post differences and Hedges’ g was used to calculate the effect size.

Results

Table 2 presents the baseline data of the sample. Change in FIQR scores (i.e., functional impact of the FM) was not predicted by any humor style, but significant effects were found for the PGIC (i.e., perceived clinical change). In the case of perceived change in physical activity, affiliative humor emerged as a significant predictor (β=−0.395, F=4.44, R2=.156, P=.046); on the other hand, the positive/negative humor style ratio was a significant predictor of perceived change in work activity (β=−0.432, F=5.51, R2=.187, P=.027), mood (β=−0.454, F=6.22, R2=.206, P=.020), and pain (β=−0.498, F=7.90, R2=.248, P=.010). In addition, self-defeatinghumor significantly predicted the perceived change in pain (β=0.467, F=6.68, R2=.218, P=.016). All these effects were preserved after controlling for the mindfulness-facets.

Table 2.

Baseline characteristics of the participants.

  Patients with FM (n=35) 
Sociodemographic outcomes
Sex, no. females (%)  34 (97.1%) 
Age, mean (SD)  54.97 (8.65) 
Years of diagnosis, mean (SD)  8.71 (6.47) 
Marital status, n (%)
Married/living with a partner  28 (82.4%) 
Separated/divorced  5 (14.7%) 
Widowed  1 (2.9%) 
Living arrangement, n (%)
Living alone  2 (5.9%) 
Living with partner  32 (94.1%) 
Education level, n (%)
Illiterate  1 (2.9%) 
Did not graduate from primary school  2 (5.9%) 
Primary school  13 (38.2%) 
Secondary school  17 (50%) 
University  1 (2.9%) 
Employment status, n (%)
Homemaker  3 (8.8%) 
Paid employment  9 (26.5%) 
Paid employment but in sick leave  2 (5.9%) 
Unemployed with subsidy  5 (14.7%) 
Unemployed without subsidy  5 (14.7%) 
Retired/pensioner  5 (14.7%) 
Temporal disability  1 (2.9%) 
Others  4 (11.8%) 
Clinical severity, humor styles and mindfulness
FIQR – Total score, mean (SD) (0–100)  58.11 (22.25) 
Physical impairment (0–30)  17.41 (7.31) 
Overall impact (0–20)  8.70 (6.79) 
Symptoms (0–50)  34 (10.42) 
HSQ, mean (SD)
Affiliative humor (8–56)  36.62 (6.67) 
Self-enhancing humor (8–56)  34.04 (9.68) 
Self-defeating humor (8–56)  20.64 (7.52) 
Aggressive humor (8–56)  18.87 (7.41) 
FFMQ-15, mean (SD)
Observing (5–15)  8.94 (2.92) 
Describing (5–15)  9.44 (2.70) 
Acting with awareness (5–15)  10.01 (2.86) 
Non-reacting (5–15)  8.66 (2.61) 
Non-judging (5–15)  10.35 (3.68) 

Note: FIQR: Fibromyalgia Impact Questionnaire – Revised; HSQ: Humor Styles Questionnaire; FFMQ-15: Five Facets Mindfulness Questionnaire – 15 item version; one patient did not attend to the first session; thus, the table presents data for 34 patients except for sex, age, and years of diagnosis.

Some significant correlations were found between humor styles, FIQR and mindfulness facets. The affiliative style presented significant negative correlations with FIQR scores (r=−.50, P=.004). No significant correlations were found with any of the mindfulness facets. The self-enhancing style presented a significant correlation with the FIQR symptoms subscale (r=−.38, P=.033), and with the mindfulness facets Describing (r=.50, P=.003), Acting with awareness (r=.37, P=.039), and Non-judging (r=.38, P=.033). The aggressive style correlated positively and significantly with the total FIQR score (r=.41, P=.021), and with the mindfulness facet Non-judging (r=−.44, P=.012). On the other hand, self-defeating humor did not correlate significantly with the FIQR nor with the FFMQ-15. Finally, when considering the humor styles ratio, significant correlations were found for the FIQR (r=−.54, P=.002) and, regarding mindfulness facets, with Acting with awareness (r=.36, P=.042) and with Non-judging (r=.58, P=.001).

Finally, and despite not being the main aim of this study, it needs to be noticed that the intervention achieved a notable degree of adherence (74% of attendance to the sessions) and was considered satisfactory (9/10), useful (8.9/10), recommendable (8.7) and non-aversive (0.5/10) by the participants in a post-treatment ad-hoc opinion survey. After the intervention, the mean FIQR score showed a significant 14% of improvement (P<.001), although the effect size was small (Hedges’ g=0.36). In the case of perceived changes after the treatment (PGIC; 1=much better, 4=no change, 7=much worse), overall small improvements were observed: mood (M=2.72, SD=1.31), social activity (M=2.93, SD=1.13), overall status (M=3.14, SD=0.83), physical activity (M=3.38, SD=0.86), work activity (M=3.41, SD=1.05), and pain (M=3.59, SD=0.91).

Discussion

To date, this is the first study to assess the predictive role of humor styles in the perceived clinical changes of a mindfulness-based intervention for FM. Our analyses indicate some predictive effects for affiliative humor, self-defeating humor, and the ratio on different areas of the perceived clinical improvement. A possible explanation could be that those patients who scored higher in positive humor styles would probably present certain personality traits (e.g. openness to experience, psychological flexibility, self-efficacy, see Martin et al.3) which could facilitate to act on the suggestions and advice given during the sessions, such as practicing aerobic exercise; on the other hand, patients with higher levels of negative humor styles could also present higher levels of depressive symptomatology, lower self-efficacy and more external locus of control,16 which could hinder learning and implementing the practices addressed to reduce pain and its consequences. Therefore, an interesting challenge would be finding ways to increase the ratio of humor styles, particularly in those cases in which the ratio is lower than 1:1 (i.e., more frequent use of negative styles). Future studies could focus on testing interventions addressed to increasing this ratio and testing the clinical implications.

To our knowledge, the present pilot study is also the first to use the FFMQ to study the relationship between mindfulness and humor styles; our results indicate that self-enhancing humor is the most strongly mindfulness-related humor style, as it has been significantly associated with multiple facets. It is possible that these associations may be related to the ability to regulate emotions and accept negative emotional states that cannot be immediately changed.6 On the other hand, aggressive humor presented a significant negative correlation with Non-judging, which is defined as refraining from judgments or self-criticism about having certain experiences (e.g., feeling anxious).

Some limitations of the present study cannot be overlooked: the small number of patients and the absence of a control group hampered analyses and reduced the robustness of the results. The lack of other clinical, coping-related and mindfulness measures administered both at pre- and at post-intervention limited the soundness of the conclusions, which in most cases have an important hypothetical base. Future studies should also evaluate other aspects of humor such as humor production or appreciation, and these studies should be conducted considering the socio-cultural differences regarding humor that some studies have already assessed.17

In conclusion, the preliminary findings of this pilot study indicate that affiliative humor and the ratio of humor styles seem to be predictors of self-reported changes after the MINDEST intervention in different areas which are relevant for FM patients (e.g., pain, work, mood). These effects could be attributed to a better disposition in patients with positive humor styles to learn and implement the concepts and resources that the intervention offered. Also, the self-enhancing humor appeared to be related to a number of mindfulness facets. Despite the considerable limitations of this study, these preliminary results contribute to knowledge on the link between humor and chronic pain and suggest some lines of research which could be undertaken in future studies.

Funding

The study has been funded in part by the Instituto de Salud Carlos III (ISCIII), Ministry of Economy and Competitiveness (Spain) through the Network for Prevention and Health Promotion in Primary Care (RD16/0007/0012), by a grant for research projects in health from ISCIII (PI15/00383) co-financed with European Union ERDF funds. The first listed author has a FI predoctoral contract awarded by the Agency for Management of University and Research Grants (AGAUR; 2017; FI_B00754). The third listed author has a “Sara Borrell” research contract from the ISCIII (CD16/00147). The fourth listed author has a FI predoctoral contract awarded by the Agency for Management of University and Research Grants (AGAUR; 2018; FI_B00783). The last listed author (JVL) has a “Miguel Servet” research contract from the ISCIII (CP14/00087).

Conflict of interest

The authors declare no conflicts of interest.

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Copyright © 2019. Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología
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