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Vol. 2. Núm. S3.
Esclerosis sistémica
Páginas S2-S5 (Noviembre 2006)
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Vol. 2. Núm. S3.
Esclerosis sistémica
Páginas S2-S5 (Noviembre 2006)
Esclerosis sistémica
Acceso a texto completo
Epidemiología. Diferencias étnicas en la esclerosis sistémica
Epidemiology. Ethnic differences in systemic sclerosis
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Jorge Rojas-Serrano
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jorroser@aol.com

Correspondencia: Dr. J. Rojas-Serrano. Instituto Nacional de Enfermedades Respiratorias. Calzada de Tlalpan 4502. Sección XVI, Tlalpan. 14080 México DF. México.
Instituto Nacional de Enfermedades Respiratorias. Tlalpan. México
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Bibliografía
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Resumen

El objetivo de esta revisión es analizar las diferencias en la epidemiología, las manifestaciones clínicas y la gravedad de la esclerosis sistémica en los diferentes grupos étnicos. La revisión se limita a la esclerosis sistémica en su variedad difusa y limitada.

Se seleccionó los artículos más relevantes del tema y se presenta la información en 3 apartados: diferencias en la epidemiología de la esclerodermia entre grupos étnicos diferentes; diferencias en la expresión clínica de la enfermedad entre grupos étnicos diferentes, y factores que pudieran explicar esas diferencias.

De los grupos étnicos estudiados, los blancos tienen menores incidencia y prevalencia de la enfermedad. Además tienen menor frecuencia de manifestaciones inflamatorias y tienden a presentar con mayor frecuencia la variedad limitada de la esclerosis sistémica. Estas diferencias se ven reflejadas en la mejor supervivencia de los blancos respecto a otros grupos étnicos. Hasta el momento, no se ha logrado identificar el origen de estas diferencias.

Es probable que factores genéticos y ambientales sean la causa de las diferencias encontradas en la expresión de la enfermedad entre los diferentes grupos étnicos estudiados.

Palabras clave:
Esclerosis sistémica difusa y limitada
Grupos étnicos
Diferencias en epidemiología y expresión clínica
Factores genéticos y ambientales
Abstract

To review the differences in the epidemiology, clinical manifestations, and severity of systemic sclerosis in different ethnic groups. This review considers only limited and diffuse forms of systemic sclerosis.

The most relevant articles about ethnic differences in systemic sclerosis were selected. The information is presented in three sections: differences in the epidemiology of systemic sclerosis between ethnic groups; differences in clinical manifestations between ethnic group, and factors that may explain these differences.

Of the different ethnic groups studied, whites have less incidence and prevalence of systemic sclerosis. Whites also have less frequency of inflammatory manifestations, and have a higher frequency of limited skin disease compared with other ethnic groups. These differences may result in the better survival of whites compared with no whites. The origin of these differences has not been discovered so far.

Is probable that genetic and environmental factors may play a role in the expression of disease, producing the differences found among the ethnic groups.

Key words:
Limited and difuse systemic sclerosis
Ethnic groups
Differences in epidemiology and clinical manifestations
Genetic and environmental factors
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Bibliografía
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Copyright © 2006. Elsevier España S.L. Barcelona
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