Información de la revista
Vol. 18. Núm. 10.
Páginas 621-622 (Diciembre 2022)
Compartir
Compartir
Descargar PDF
Más opciones de artículo
Visitas
544
Vol. 18. Núm. 10.
Páginas 621-622 (Diciembre 2022)
Images in Clinical Rheumatology
Acceso a texto completo
‘Vasculitic lung lesions’ – Don’t forget the heart!
‘Lesiones pulmonares vasculíticas’ – ¡No olvides el corazón!
Visitas
544
Joydeep Samantaa, Arghya Chattopadhyaya, Varun Dhirb,
Autor para correspondencia
varundhir@gmail.com

Corresponding author.
a Senior Resident, Clinical Immunology and Rheumatology Unit, Post Graduate Institute of Medical Education and Research, Chandigarh, Punjab, India
b Additional Professor, Clinical Immunology and Rheumatology Unit, Post Graduate Institute of Medical Education and Research, Chandigarh, Punjab, India
Este artículo ha recibido
Información del artículo
Texto completo
Bibliografía
Descargar PDF
Estadísticas
Figuras (1)
Texto completo

A 55-year-old-woman, presented with complaints of exertional dyspnea for 6 months, numbness of legs for 4 months and low-grade intermittent fever for 2 months. She had a ventricular septal defect (VSD) first detected 20 years ago. Examination revealed a pansystolic murmur in neoaortic area, slightly decreased power in right lower limb, but normal deep tendon reflexes. Blood tests revealed moderate anaemia, high erythrocyte sedimentation rate and elevated C-reactive protein. Contrast enhanced computed tomography of chest showed multiple irregular nodules in both lung with central cavitation and surrounding consolidation (Fig. 1A and B). Her blood cultures were sterile, nerve conduction study showed right peroneal motor axonal neuropathy, and transthoracic echocardiograph showed moderate VSD, mild aortic and mitral regurgitations but no vegetations. Anti-neutrophil cytoplasmic (ANCA) vasculitis was considered a strong possibility, however, ANCA against proteinase 3 and myeloperoxidase was negative. In this scenario, a reassessment of possibilities and applying Occam's razor, infective endocarditis was reconsidered, and transesophageal echocardiography revealed moderate VSD (9mm) with left to right shunt, one mobile vegetation (10.7mm) on non-coronary cusp of the aortic valve and one on (11.6mm) right side of inter-ventricular septum with severe aortic regurgitation (1C and D). A diagnosis of infective endocarditis with septic pulmonary embolism was made. She received four weeks of parenteral antibiotics, followed by repair of VSD, aortic valve replacement and mitral valve repair, and is doing well. Infective endocarditis (especially culture negative) can often masquerade as vasculitis.1,2

Fig. 1.

(A and B) Contrast enhanced computed tomography of chest showed multiple irregular nodules in both lung with central cavitation and surrounding consolidation. (C and D) Transthoracic echocardiography showing ventricular septal defect with two vegetations on non-coronary cusp and right side of interventricular septum.

(0,71MB).
Consent

Written consent has been obtained from the patient for the publication.

Financial disclosures/funding sources

None of the authors has any financial disclosure or funding sources.

Conflict of interests

The authors declare that they have no conflict of interest.

References
[1]
M. Reza Ardalan, M. Trillini.
Infective endocarditis mimics ANCA associated glomerulonephritis.
Caspian J Intern Med, 3 (2012), pp. 496-499
[2]
H. Sugiyama, M. Sahara, Y. Imai, M. Ono, K. Okamoto, K. Kikuchi, et al.
Infective endocarditis by Bartonella quintana masquerading as antineutrophil cytoplasmic antibody-associated small vessel vasculitis.
Cardiology, 114 (2009), pp. 208-211
Copyright © 2022. Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología
Idiomas
Reumatología Clínica
Opciones de artículo
Herramientas
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?